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CAS 1234015-63-4
5-bromo-N-(5-(2-methoxy-6-((4-methoxybenzyl)oxy)phenyl)-1H-pyrazol-3-yl)pyrazin-2-amine
Codes: PREXA-011
Application context (from source-drug indications)
Head and neck squamous cell carcinomaPrexasertibEndometrial cancerPrexasertib三阴性乳腺癌Prexasertib脑癌Prexasertib髓母细胞瘤Prexasertib中枢神经系统肿瘤Prexasertib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Prexasertib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(2-hydroxy-6-methoxyphenyl)ethan-1-one→1-(2-methoxy-6-((4-methoxybenzyl)oxy)phenyl)ethan-1-one→5-bromopyrazin-2-amine→5-bromo-N-(5-(2-methoxy-6-((4-methoxybenzyl)oxy)phenyl)-1H-pyrazol-3-yl)pyrazin-2-amine→2-(3-((5-bromopyrazin-2-yl)amino)-1H-pyrazol-5-yl)-3-methoxyphenol→tert-butyl (3-(2-(3-((5-bromopyrazin-2-yl)amino)-1H-pyrazol-5-yl)-3-methoxyphenoxy)propyl)carbamate
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