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CAS 1234208-02-6
tert-butyl (E)-(4-(2-(6-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)pyridin-3-yl)vinyl)phenyl)(methyl)carbamate
Codes: FLORB-005
Application context (from source-drug indications)
Alzheimer's diseaseFlorbetapir(18F)Contrast imagingFlorbetapir(18F)GlioblastomaFlorbetapir(18F)Neurodegenerative diseaseFlorbetapir(18F)Frontotemporal dementiaFlorbetapir(18F)Mild cognitive impairmentFlorbetapir(18F)
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Florbetapir(18F) | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2,2'-(ethane-1,2-diylbis(oxy))bis(ethan-1-ol)→2-bromo-5-iodopyridine→2-(2-(2-((5-iodopyridin-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol→tert-butyl methyl(4-vinylphenyl)carbamate→tert-butyl (E)-(4-(2-(6-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)pyridin-3-yl)vinyl)phenyl)(methyl)carbamate→(E)-2-(2-(2-((5-(4-((tert-butoxycarbonyl)(methyl)amino)styryl)pyridin-2-yl)oxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate→4-vinylaniline→tert-butyl (4-vinylphenyl)carbamate
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