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CAS 1255908-99-6
3-Nitro-5-[1(S)-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]thieno[3,4-c]pyrrole-4,6-dione
Codes: (VIII)989842-1-a
Application context (from source-drug indications)
Plaque psoriasisMufemilastUlcerative colitisMufemilastBehçet's syndromeMufemilastPsoriasisMufemilastChronic obstructive pulmonary diseaseMufemilastAtopic dermatitisMufemilast
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Mufemilast | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3,4-Bis(bromanyl)thiophene→3,4-Dicyanothiophene→Thiophene-3,4-dicarboxylic acid→1H,3H-Thieno[3,4-c]furan-1,3-dione→2-Nitrothiophene-3,4-dicarboxylic acid→4-Nitro-1H,3H-thieno[3,4-c]furan-1,3-dione→(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine→3-Nitro-5-[1(S)-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]thieno[3,4-c]pyrrole-4,6-dione→1-Amino-5-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methanesulfonyl)ethyl]-4H-thieno[3,4-c]pyrrole-4,6(5H)-dione→Acetic acid acetic anhydride→Acetic acid chloride
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