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CAS 1282518-60-8
1-isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Codes: GTx-011-001
Application context (from source-drug indications)
Sickle cell diseaseVoxelotorHaemolytic anaemiaVoxelotorNephropathyVoxelotorLeg ulcerVoxelotorAcute lung injuryVoxelotorInterstitial lung diseaseVoxelotor
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Voxelotor | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole→(2-chloropyridin-3-yl)methanol→(2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methanol→3-(chloromethyl)-2-(1-isopropyl-1H-pyrazol-5-yl)pyridine→2-hydroxy-6-(methoxymethoxy)benzaldehyde→2-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)-6-(methoxymethoxy)benzaldehyde→2-bromobenzene-1,3-diol→2-bromo-1,3-bis(methoxymethoxy)benzene→2,6-bis(methoxymethoxy)benzaldehyde
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | 1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.