← Back to patent-cliff list
CAS 1289942-66-0
2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid
Codes: ENZA-011
Application context (from source-drug indications)
Hormone-sensitive prostate cancerEnzalutamideCastration-resistant prostate cancerEnzalutamideProstate cancerEnzalutamide
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Enzalutamide | Tier A — Act now | 2027 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-isothiocyanato-2-(trifluoromethyl)benzonitrile→4-bromo-2-fluorobenzoic acid→4-bromo-2-fluoro-N-methylbenzamide→2-amino-2-methylpropanoic acid→2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid→methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate
2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid→4-amino-2-(trifluoromethyl)benzonitrile→4-((1-((4-cyano-3-(trifluoromethyl)phenyl)amino)-2-methyl-1-oxopropan-2-yl)amino)-2-fluoro-N-methylbenzamide
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.