← Back to patent-cliff list
CAS 1297537-45-1
5-acetyl-1H-pyrazole-3-carboxylic acid
Codes: ODM-201-008
Application context (from source-drug indications)
Hormone-sensitive prostate cancerDarolutamideCastration-sensitive prostate cancerDarolutamideProstate cancerDarolutamideCastration-resistant prostate cancerDarolutamide
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Darolutamide | Tier B — Position early | 2031 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-bromo-2-chlorobenzonitrile→1-(tetrahydro-2H-pyran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole→2-chloro-4-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)benzonitrile→2-chloro-4-(1H-pyrazol-3-yl)benzonitrile hydrochloride→2-chloro-4-(1H-pyrazol-3-yl)benzonitrile→tert-butyl (S)-(1-hydroxypropan-2-yl)carbamate→(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile→5-acetyl-1H-pyrazole-3-carboxylic acid→(S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Qualified Partner — East China API Works | 4-Bromo-2-chlorobenzonitrile Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.