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CAS 132245-51-3
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl cyclopropanecarboxylate
Codes: DEXA-003
Application context (from source-drug indications)
Allergic rhinitisDexamethasone CipecilateSeasonal allergic rhinitisDexamethasone CipecilateMultiple myelomaDexamethasone CipecilateT-lymphoblastic lymphoma/leukaemiaDexamethasone CipecilateLiver cancerDexamethasone CipecilateSolid tumourDexamethasone Cipecilate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Dexamethasone Cipecilate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one→(trimethoxymethyl)cyclopropane→(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl cyclopropanecarboxylate→cyclohexanecarbonyl chloride
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