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CAS 132684-60-7
(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3,3-dimethylbutanoic acid
Codes: TELAP-050
Application context (from source-drug indications)
Hepatitis CTelaprevirChronic hepatitis CTelaprevirHIV infectionTelaprevirHepatic function declineTelaprevirOpioid dependenceTelaprevirKidney diseaseTelaprevir
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Telaprevir | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
pyrazine-2-carboxylic acid→cyclopropanamine→1-nitrobutane→2-oxoacetic acid→(3S)-2-hydroxy-3-nitrohexanoic acid→(3S)-3-amino-2-hydroxyhexanoic acid→(3S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-hydroxyhexanoic acid→(S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-oxohexanoic acid→TELAP-046→TELAP-047→(1S,3aR,6aS)-2-(((9H-fluoren-9-yl)methoxy)carbonyl)octahydrocyclopenta[c]pyrrole-1-carboxylic acid→TELAP-049→(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3,3-dimethylbutanoic acid→TELAP-051→(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-cyclohexylacetic acid→TELAP-053→TELAP-054→(S)-3-((1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)octahydrocyclopenta[c]pyrrole-1-carboxamido)-2-oxohexanoic acid
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