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CAS 133860-61-4
4-nitrophenyl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate
Codes: PEGL-008
Application context (from source-drug indications)
Type 2 diabetesPEG-LoxenatideObesityPEG-LoxenatideEndometrial hyperplasiaPEG-Loxenatide
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| PEG-Loxenatide | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(2-methoxyethoxy)ethan-1-ol→2-(2-methoxyethoxy)ethyl carbonochloridate→2,5-dioxopyrrolidin-1-yl (2-(2-methoxyethoxy)ethyl) carbonate→15-(((2-(2-methoxyethoxy)ethoxy)carbonyl)amino)-9-oxo-2,5,8-trioxa-10-azahexadecan-16-oic acid→2,5-dioxopyrrolidin-1-yl 15-(((2-(2-methoxyethoxy)ethoxy)carbonyl)amino)-9-oxo-2,5,8-trioxa-10-azahexadecan-16-oate→ethane-1,2-diamine→bis(2-(2-methoxyethoxy)ethyl) (6-((2-aminoethyl)amino)-6-oxohexane-1,5-diyl)dicarbamate→4-nitrophenyl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate→bis(2-(2-methoxyethoxy)ethyl) (6-((2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethyl)amino)-6-oxohexane-1,5-diyl)dicarbamate
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