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CAS 1341207-62-2

2,2',2''-(10-[2-[([4-[(3-[(2R,5S,8S,14R)-5-(3-Carbamimidamidopropyl)-14-[(4-hydroxyphenyl)methyl]-1-methyl-8-[(naphthalen-2-yl)methyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl]propyl)carbamoyl]phenyl]methyl)amino]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid

Codes: (XXI)755707-1-e

Application context (from source-drug indications)

Cushing's syndrome68Ga-pentixafor醛固酮增多症68Ga-pentixaforSarcoidosis68Ga-pentixaforGraft-versus-host disease68Ga-pentixaforNeuroendocrine tumour68Ga-pentixaforMarginal zone B-cell lymphoma68Ga-pentixafor

Source drugs (routes using this intermediate)

DrugTierExpiry
68Ga-pentixaforTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

68Ga-pentixaforOptimised routesteps: 4total yield: /
Tri-tert-butyl 2,2',2''-[10-[2-([[4-([3-[(2R,5S,8S,14R)-14-[(4-tert-butoxyphenyl)methyl]-1-methyl-8-[(naphthalen-2-yl)methyl]-3,6,9,12,15-pentaoxo-5-[3-[N'-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-sulfonyl)carbamimidamido]propyl]-1,4,7,10,13-pentaazacyclopentadecan-2-yl]propyl]carbamoyl)phenyl]methyl]amino)-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetate→2,2',2''-(10-[2-[([4-[(3-[(2R,5S,8S,14R)-5-(3-Carbamimidamidopropyl)-14-[(4-hydroxyphenyl)methyl]-1-methyl-8-[(naphthalen-2-yl)methyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl]propyl)carbamoyl]phenyl]methyl)amino]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid

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