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CAS 13726-52-8
N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester
Codes: Folic Acid-006
Application context (from source-drug indications)
Essential hypertensionEnalapril Maleate/Folic AcidMegaloblastic anaemiaFolic AcidFolate deficiencyFolic AcidNeural tube defectFolic AcidAnaemiaFolic AcidHot flushesFolic AcidHyperhomocysteinaemiaFolic Acid
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Enalapril Maleate/Folic Acid | Tier C — Watch / trade | - |
| Folic Acid | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(2-Amino-4-oxo-3,4-dihydropteridin-6-ylmethyl)pyridinium iodide→2-Amino-6-methyl-3,4,5,8-tetrahydropteridin-4-one→2-Amino-6-methylpteridin-4(3H)-one→2-Amino-6-(chloromethyl)pteridin-4(3H)-one→2-Amino-6-(bromomethyl)pteridin-4(3H)-one→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→N-[4-(2-Amino-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid diethyl diester
2,3-Dihydroxy-2-propenal→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→N-[4-[2,3-Dihydroxy-2-propenylideneamino]benzoyl]-L-glutamic acid diethyl diester→2,5,6-Triaminopyrimidin-4(5H)-one
N-(4-Aminobenzoyl)-L-glutamic acid→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→2,3-Dibromopropanal→N-[4-(2,3-Dibromopropylideneamino)benzoyl]-L-glutamic acid diethyl diester→2,5,6-Triaminopyrimidin-4(5H)-one→N-[4-(2-Amino-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid diethyl diester
1-(2-Amino-4-oxo-3,4-dihydropteridin-6-ylmethyl)pyridinium iodide→2-Amino-6-methyl-3,4,5,8-tetrahydropteridin-4-one→2-Amino-6-methylpteridin-4(3H)-one→2-Amino-6-(chloromethyl)pteridin-4(3H)-one→2-Amino-6-(bromomethyl)pteridin-4(3H)-one→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→N-[4-(2-Amino-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid diethyl diester
2,3-Dihydroxy-2-propenal→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→N-[4-[2,3-Dihydroxy-2-propenylideneamino]benzoyl]-L-glutamic acid diethyl diester→2,5,6-Triaminopyrimidin-4(5H)-one
N-(4-Aminobenzoyl)-L-glutamic acid→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→2,3-Dibromopropanal→N-[4-(2,3-Dibromopropylideneamino)benzoyl]-L-glutamic acid diethyl diester→2,5,6-Triaminopyrimidin-4(5H)-one→N-[4-(2-Amino-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid diethyl diester
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