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CAS 1389253-14-8
ethyl (4-chloro-2-(2,2,2-trifluoroacetyl)phenyl)carbamate
Codes: EFAV-029
Application context (from source-drug indications)
HIV infectionEfavirenz/Lamivudine/Tenofovir Disoproxil FumarateHIV infectionEfavirenzCreutzfeldt-Jakob diseaseEfavirenzAlzheimer's diseaseEfavirenzPancreatic cancerEfavirenzProstate cancerEfavirenzNon-Hodgkin lymphomaEfavirenz
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Efavirenz/Lamivudine/Tenofovir Disoproxil Fumarate | Tier C — Watch / trade | - |
| Efavirenz | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ethynylcyclopropane→1-(2-amino-5-chlorophenyl)-2,2,2-trifluoroethanone hydrochloride→ethyl carbonochloridate→ethyl (4-chloro-2-(2,2,2-trifluoroacetyl)phenyl)carbamate→(1R,2R)-2-(benzyl(methyl)amino)-3-(tert-butoxy)-1-(4-nitrophenyl)propan-1-ol→(1R,2R)-2-(benzyl(methyl)amino)-1-(4-nitrophenyl)propane-1,3-diol→2-methylprop-1-ene
ethynylcyclopropane→1-(2-amino-5-chlorophenyl)-2,2,2-trifluoroethanone hydrochloride→ethyl carbonochloridate→ethyl (4-chloro-2-(2,2,2-trifluoroacetyl)phenyl)carbamate→(1R,2R)-2-(benzyl(methyl)amino)-3-(tert-butoxy)-1-(4-nitrophenyl)propan-1-ol→(1R,2R)-2-(benzyl(methyl)amino)-1-(4-nitrophenyl)propane-1,3-diol→2-methylprop-1-ene
Intermediates available on this site
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