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CAS 1414840-15-5
2-(3,5-Dichlorophenyl)-6-methyl-1,3-benzoxazole
Codes: (IIIa)409139-7-a, (VI)409139-12-a
Application context (from source-drug indications)
Transthyretin amyloidosisTafamidisHeart diseaseTafamidis
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Tafamidis | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3,5-Dichlorobenzaldehyde→3,5-Dichlorobenzoic acid→2-Amino-5-methylphenol→1-Amino-2-hydroxy-4-ethylbenzene→2-Amino-5-butylphenol→(4-Carboxy-2-hydroxyphenyl)amine→2-(3,5-Dichlorophenyl)-6-methyl-1,3-benzoxazole→2-(3,5-Dichlorophenyl)-6-ethyl-1,3-benzoxazole→6-Butyl-2-(3,5-dichlorophenyl)-1,3-benzoxazole→2-(3,5-Dichlorophenyl)benzo[d]oxazole-6-carboxylic acid→4-([(1E)-(3,5-Dichlorophenyl)methylene]amino)-3-hydroxybenzoic acid
3,5-Dichloroaniline→2,3-Butanedione→1-(3,5-Dichlorophenyl)ethanone→(3,5-Dichlorophenyl)(oxo)acetic acid→2-Amino-5-methylphenol→2-(3,5-Dichlorophenyl)-6-methyl-1,3-benzoxazole→2-(3,5-Dichlorophenyl)benzo[d]oxazole-6-carboxylic acid
Intermediates available on this site
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