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CAS 1415796-11-0

4-((6-amino-5-bromo-2-chloropyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile

Codes: ETRA-023

Application context (from source-drug indications)

HIV infectionEtravirineFriedreich's ataxiaEtravirineInflammatory diseaseEtravirineInsulin resistanceEtravirine

Source drugs (routes using this intermediate)

DrugTierExpiry
EtravirineTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

EtravirineOptimised routesteps: 3total yield: 379 mg
4-aminobenzonitrile→4-hydroxy-3,5-dimethylbenzonitrile→2,6-dichloropyrimidin-4-amine→5-bromo-2,6-dichloropyrimidin-4-amine→4-((6-amino-5-bromo-2-chloropyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile

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