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CAS 14191-95-8
2-(4-hydroxyphenyl)acetonitrile2-(4-Hydroxyphenyl)acetonitrile
Codes: DESV-016, Desvenlafaxine-017
Application context (from source-drug indications)
Depressive disorderDesvenlafaxine Succinate HydrateMajor depressive disorderDesvenlafaxine Succinate HydrateDepressionDesvenlafaxine Succinate HydrateDiabetic neuropathyDesvenlafaxine Succinate HydratePainDesvenlafaxine Succinate HydrateFibromyalgiaDesvenlafaxine Succinate HydrateMajor depressive disorderDesvenlafaxineDepressive disorderDesvenlafaxine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Desvenlafaxine Succinate Hydrate | Tier C — Watch / trade | - |
| Desvenlafaxine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-(2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol→2-(4-hydroxyphenyl)acetonitrile→DESV-017→2-(1-hydroxycyclohexyl)-2-(4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)acetonitrile→1-(2-amino-1-(4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)ethyl)cyclohexan-1-ol→DESV-020
4-(2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol→cyclohexanone→2-(4-methoxyphenyl)acetonitrile→2-(4-hydroxyphenyl)acetonitrile→DESV-021
2-(4-Hydroxyphenyl)acetonitrile→Cyclohexanone→(1-Hydroxycyclohexyl)(4-hydroxyphenyl)acetonitrile→4-[2-Amino-1-(1-hydroxycyclohexyl)ethyl]phenol→2-[4-(Oxan-2-yloxy)phenyl]acetonitrile→[4-(Benzyloxy)phenyl]acetonitrile→2-(1-Hydroxycyclohexyl)-2-[4-(oxan-2-yloxy)phenyl]acetonitrile→[4-(Benzyloxy)phenyl](1-hydroxycyclohexyl)acetonitrile→Iodomethane→4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol
2-(4-Methoxyphenyl)acetonitrile→2-(4-Hydroxyphenyl)acetonitrile→[4-[(2-Methoxyethoxy)methoxy]phenyl]acetonitrile→Cyclohexanone→(1-Hydroxycyclohexyl)[4-[(2-methoxyethoxy)methoxy]phenyl]acetonitrile→Dimethylamine hydrochloride→Desvenlafaxine-036→4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol→(1-Hydroxycyclohexyl)(4-hydroxyphenyl)acetonitrile
Intermediates available on this site
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.