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CAS 1421312-33-5
methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
Codes: ROXA-018
Application context (from source-drug indications)
AnaemiaRoxadustat
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Roxadustat | Tier C — Watch / trade | 2028 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-phenoxyphthalic acid→4-nitrophthalonitrile→4-phenoxyphthalonitrile→5-phenoxyisobenzofuran-1,3-dione→methyl 2-cyanoacetate→2-(4-(methoxycarbonyl)oxazol-5-yl)-4-phenoxybenzoic acid→methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate→methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate→methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate→4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid→methyl glycinate hydrochloride→methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | 4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.