CAS 142470-47-1

5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole

Codes: S-pantoprazole sodium-005

Application context (from source-drug indications)

Gastro-oesophageal reflux diseaseS-pantoprazole sodiumPeptic ulcerS-pantoprazole sodiumHaemorrhageS-pantoprazole sodiumTrauma and injuryS-pantoprazole sodiumComaS-pantoprazole sodiumAspiration pneumoniaS-pantoprazole sodium

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
S-pantoprazole sodium	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

S-pantoprazole sodiumOptimised routesteps: 3total yield: 4g((S)-(-)-Pantoprazole sodium (API))

potassium (ethoxymethanethioyl)sulfanide→1,2-Diamino-4-(difluoromethoxy)benzene→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→2-(chloromethyl)-3,4-dimethoxypyridine→5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole

Intermediates available on this site

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