← Back to patent-cliff list
CAS 1427156-21-5
(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-13-[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-(1-ethoxyethoxy)-3-phenylpropanoyl]oxy]-1-hydroxy-9-oxo-7,10-bis(trityloxy)-5,20-epoxytax-11-en-2-yl benzoate
Codes: (IV)140605-29-a
Application context (from source-drug indications)
Bladder cancerDocetaxel polymeric micelle (Samyang Biopharmaceuticals)Head and neck cancerDocetaxel polymeric micelle (Samyang Biopharmaceuticals)Head and neck squamous cell carcinomaDocetaxel polymeric micelle (Samyang Biopharmaceuticals)Solid tumourDocetaxel polymeric micelle (Samyang Biopharmaceuticals)Non-small cell lung cancerDocetaxel （Beihai）Prostate cancerDocetaxel （Beihai）Castration-resistant prostate cancerDocetaxel （Beihai）Breast cancerDocetaxel （Beihai）Head and neck cancerDocetaxel （Beihai）Head and neck squamous cell carcinomaDocetaxel （Beihai）
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Docetaxel polymeric micelle (Samyang Biopharmaceuticals) | Tier C — Watch / trade | - |
| Docetaxel （Beihai） | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(2alpha,5beta,7beta,10beta,13alpha)-4-(Acetyloxy)-1,7,10,13-tetrahydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate→(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-1,13-dihydroxy-9-oxo-7,10-bis(trityloxy)-5,20-epoxytax-11-en-2-yl benzoate→3(R)-(1-Ethoxyethoxy)-2-oxo-4(S)-phenylazetidine-1-carboxylic acid tert-butyl ester→(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-13-[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-(1-ethoxyethoxy)-3-phenylpropanoyl]oxy]-1-hydroxy-9-oxo-7,10-bis(trityloxy)-5,20-epoxytax-11-en-2-yl benzoate→(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-13-[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-(1-ethoxyethoxy)-3-phenylpropanoyl]oxy]-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
(2alpha,5beta,7beta,10beta,13alpha)-4-(Acetyloxy)-1,7,10,13-tetrahydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate→(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-1,13-dihydroxy-9-oxo-7,10-bis(trityloxy)-5,20-epoxytax-11-en-2-yl benzoate→3(R)-(1-Ethoxyethoxy)-2-oxo-4(S)-phenylazetidine-1-carboxylic acid tert-butyl ester→(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-13-[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-(1-ethoxyethoxy)-3-phenylpropanoyl]oxy]-1-hydroxy-9-oxo-7,10-bis(trityloxy)-5,20-epoxytax-11-en-2-yl benzoate→(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-13-[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-(1-ethoxyethoxy)-3-phenylpropanoyl]oxy]-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.