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CAS 1431364-31-6

3-Iodo-7-methoxyquinolin-4-ol

Codes: (II)1078735-4-a

Application context (from source-drug indications)

Breast cancerImlunestrant TosylateMetastatic breast cancerImlunestrant TosylateMetastatic cancerImlunestrant TosylateOvarian cancerImlunestrant TosylateEndometrial cancerImlunestrant TosylateColorectal cancerImlunestrant Tosylate

Source drugs (routes using this intermediate)

DrugTierExpiry
Imlunestrant TosylateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Imlunestrant TosylateOptimised routesteps: 2total yield: /
4-Hydroxy-7-methoxyquinoline-3-carboxylic acid→3-Iodo-7-methoxyquinolin-4-ol→[2-Fluoro-4-(trifluoromethyl)phenyl]boronic acid→3-[2-Fluoro-4-(trifluoromethyl)phenyl]-7-methoxyquinolin-4-ol

Intermediates available on this site

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