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CAS 143163-70-6
2-(bromomethyl)-5-fluorobenzo[d]thiazole
Codes: Yogliptin-004
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Yogliptin | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
8-bromo-3-methyl-3,7-dihydro-1H-purine-2,6-dione→1-bromobut-2-yne→8-bromo-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione→2-(bromomethyl)-5-fluorobenzo[d]thiazole→8-bromo-7-(but-2-yn-1-yl)-1-((5-fluorobenzo[d]thiazol-2-yl)methyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione→tert-butyl (R)-piperidin-3-ylcarbamate→tert-butyl (R)-(1-(7-(but-2-yn-1-yl)-1-((5-fluorobenzo[d]thiazol-2-yl)methyl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate
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