← Back to patent-cliff list
CAS 1443531-74-5
(4-amino-5,7-dibromopyrrolo[2,1-f][1,2,4]triazin-6-yl)methanol
Codes: ROGAR-015
Application context (from source-drug indications)
SarcomaRogaratinibGastrointestinal stromal tumourRogaratinibBreast cancerRogaratinibMetastatic breast cancerRogaratinibNon-small cell lung cancerRogaratinibUrothelial carcinomaRogaratinib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Rogaratinib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(7-methoxy-5-methylbenzo[b]thiophen-2-yl)boronic acid→piperazin-2-one→(4-aminopyrrolo[2,1-f][1,2,4]triazin-6-yl)methanol→(4-amino-5,7-dibromopyrrolo[2,1-f][1,2,4]triazin-6-yl)methanol→(4-amino-5-bromopyrrolo[2,1-f][1,2,4]triazin-6-yl)methanol→2-(7-methoxy-5-methylbenzo[b]thiophen-2-yl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione→(4-amino-5-(7-methoxy-5-methylbenzo[b]thiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl)methanol→5-(7-methoxy-5-methylbenzo[b]thiophen-2-yl)-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine→2,2'-(methylazanediyl)diacetic acid→4-((4-amino-5-(7-methoxy-5-methylbenzo[b]thiophen-2-yl)-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl)methyl)piperazin-2-one
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.