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CAS 1446701-97-8
methyl 4-((2-aminopyrimidin-4-yl)amino)-3,5-dimethylbenzoate
Codes: RILP-022
Application context (from source-drug indications)
HIV infectionRilpivirine HydrochlorideHepatic function declineRilpivirine HydrochlorideAcquired immunodeficiency syndromeRilpivirine HydrochlorideContraceptive useRilpivirine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Rilpivirine Hydrochloride | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-bromopyrimidin-2-amine→(E)-3-(4-((2-aminopyrimidin-4-yl)amino)-3,5-dimethylphenyl)acrylonitrile→4-bromobenzonitrile→methyl 4-amino-3,5-dimethylbenzoate→methyl 4-((2-((tert-butoxycarbonyl)amino)pyrimidin-4-yl)amino)-3,5-dimethylbenzoate→methyl 4-((2-aminopyrimidin-4-yl)amino)-3,5-dimethylbenzoate→(4-((2-aminopyrimidin-4-yl)amino)-3,5-dimethylphenyl)methanol→4-((2-aminopyrimidin-4-yl)amino)-3,5-dimethylbenzaldehyde→(cyanomethyl)triphenylphosphonium chloride
Intermediates available on this site
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