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CAS 146-78-1

(2R,3R,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Codes: REGA-011

Application context (from source-drug indications)

Cardiovascular contrast agentRegadenoson HydrateDiagnostic agentRegadenoson HydrateContrast imagingRegadenoson HydrateCoronary artery lesionRegadenoson HydrateIschaemic heart diseaseRegadenoson HydratePneumoniaRegadenoson Hydrate

Source drugs (routes using this intermediate)

DrugTierExpiry
Regadenoson HydrateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

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Regadenoson HydrateOptimised routesteps: 2total yield: 3 g
ethyl 1H-pyrazole-4-carboxylate→N-methyl-1H-pyrazole-4-carboxamide→(2R,3R,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

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