← Back to patent-cliff list
CAS 14618-80-5
(R)-2-((benzyloxy)methyl)oxirane(2R)-2-(Phenylmethoxymethyl)oxirane
Codes: SAFI-023, Mosapride Citrate-039
Application context (from source-drug indications)
Parkinson's diseaseSafinamide MesylatePainSafinamide MesylateDrug-induced dyskinesiaSafinamide MesylateHepatic function declineSafinamide MesylateMultiple system atrophySafinamide MesylateRenal impairmentSafinamide MesylateGastritisMosapride CitrateEnteral feeding intoleranceMosapride CitrateIrritable bowel syndromeMosapride CitrateDyspepsiaMosapride CitrateConstipationMosapride Citrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Safinamide Mesylate | Tier C — Watch / trade | - |
| Mosapride Citrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-fluoro-3-(iodomethyl)benzene→4-(hydroxymethyl)phenol→(4-((3-fluorobenzyl)oxy)phenyl)methanol→1-fluoro-3-((4-(iodomethyl)phenoxy)methyl)benzene→SAFI-018→SAFI-019→SAFI-020→SAFI-021→2-((benzyloxy)methyl)oxirane→(R)-2-((benzyloxy)methyl)oxirane→(R)-1-(benzyloxy)propan-2-ol→(S)-((2-azidopropoxy)methyl)benzene→(S)-2-aminopropan-1-ol
[(2R)-4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl phenylmethanesulfonate→(2R)-2-(Phenylmethoxymethyl)oxirane→Sodium (2-aminoethyl) sulfate→2(R)-(Benzyloxymethyl)morpholine→(2R)-morpholin-2-ylmethanol→1-(Chloromethyl)-4-fluorobenzene→{4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl 4-methylbenzene-1-sulfonate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.