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CAS 147-94-4

4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

Codes: MB07133-010

Application context (from source-drug indications)

Liver cancerPracytarabineHepatocellular carcinomaPracytarabine线粒体疾病PracytarabineCholangiocarcinomaPracytarabine

Source drugs (routes using this intermediate)

DrugTierExpiry
PracytarabineTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

PracytarabineOptimised routesteps: 2total yield: 1.38 g
(S)-1-(pyridin-4-yl)propane-1,3-diol→(2S,4S)-2-chloro-4-(pyridin-4-yl)-1,3,2-dioxaphosphinane 2-oxide→4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

Intermediates available on this site

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