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CAS 14907-27-8
(R)-methyl 2-amino-3-(1H-indol-3-yl)propanoate hydrochloride
Codes: ANAM-002
Application context (from source-drug indications)
CachexiaAnamorelin HydrochlorideNon-small cell lung cancerAnamorelin HydrochlorideBreast cancerAnamorelin HydrochlorideLung cancerAnamorelin Hydrochloride厌食Anamorelin HydrochlorideFatigueAnamorelin Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Anamorelin Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-((tert-butoxycarbonyl)amino)-2-methylpropanoic acid→(R)-methyl 2-amino-3-(1H-indol-3-yl)propanoate hydrochloride→(R)-methyl 2-(2-((tert-butoxycarbonyl)amino)-2-methylpropanamido)-3-(1H-indol-3-yl)propanoate→(R)-2-(2-((tert-butoxycarbonyl)amino)-2-methylpropanamido)-3-(1H-indol-3-yl)propanoic acid→(3R)-3-benzyl-N,N',N'-trimethylpiperidine-3-carbohydrazide;dihydrochloride→tert-butyl (1-(((R)-1-((R)-3-benzyl-3-(1,2,2-trimethylhydrazinecarbonyl)piperidin-1-yl)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-2-methyl-1-oxopropan-2-yl)carbamate
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