← Back to patent-cliff list
CAS 149289-29-2
4-[2-Amino-1-(1-hydroxycyclohexyl)ethyl]phenol
Codes: Desvenlafaxine-019
Application context (from source-drug indications)
Major depressive disorderDesvenlafaxineDepressive disorderDesvenlafaxine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Desvenlafaxine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(4-Hydroxyphenyl)acetonitrile→Cyclohexanone→(1-Hydroxycyclohexyl)(4-hydroxyphenyl)acetonitrile→4-[2-Amino-1-(1-hydroxycyclohexyl)ethyl]phenol→2-[4-(Oxan-2-yloxy)phenyl]acetonitrile→[4-(Benzyloxy)phenyl]acetonitrile→2-(1-Hydroxycyclohexyl)-2-[4-(oxan-2-yloxy)phenyl]acetonitrile→[4-(Benzyloxy)phenyl](1-hydroxycyclohexyl)acetonitrile→Iodomethane→4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol
2-(1-Hydroxycyclohexyl)-2-(4-methoxyphenyl)acetonitrile→1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride→1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol→4-[2-Amino-1-(1-hydroxycyclohexyl)ethyl]phenol→4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol→1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol→1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
3-(4-Hydroxyphenyl)propanenitrile→Cyclohexanone→3-Cyclohexylidene-3-(4-hydroxyphenyl)propanenitrile→[2-(4-Hydroxyphenyl)-1-oxaspiro[2.5]octan-2-yl]acetonitrile→4-[2-Amino-1-(1-hydroxycyclohexyl)ethyl]phenol→4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.