← Back to patent-cliff list
CAS 1510155-99-3
2-Amino-4-(methoxycarbonyl)thiophene-3-carboxylic acid
Codes: (II)989842-2-a
Application context (from source-drug indications)
Plaque psoriasisMufemilastUlcerative colitisMufemilastBehçet's syndromeMufemilastPsoriasisMufemilastChronic obstructive pulmonary diseaseMufemilastAtopic dermatitisMufemilast
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Mufemilast | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-tert-Butyl 4-methyl 2-aminothiophene-3,4-dicarboxylate→3-Benzyl 4-methyl 2-aminothiophene-3,4-dicarboxylate→2-Amino-4-(methoxycarbonyl)thiophene-3-carboxylic acid→(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine→Methyl 5-amino-4-[[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methanesulfonyl)ethyl]carbamoyl]thiophene-3-carboxylate→Acetic acid acetic anhydride→Acetic acid chloride→Methyl 5-acetamido-4-[[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methanesulfonyl)ethyl]carbamoyl]thiophene-3-carboxylate→5-Acetamido-4-[[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methanesulfonyl)ethyl]carbamoyl]thiophene-3-carboxylic acid
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.