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CAS 153334-07-7
2-[2-(2-Ethoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione
Codes: Tamsulosin Hydrochloride-064
Application context (from source-drug indications)
Erectile dysfunctionTadalafil/TamsulosinBenign prostatic hyperplasiaTadalafil/TamsulosinLower urinary tract symptomsSolifenacin Succinate/Tamsulosin HydrochlorideBenign prostatic hyperplasiaSolifenacin Succinate/Tamsulosin HydrochlorideOveractive bladderSolifenacin Succinate/Tamsulosin HydrochlorideDrug-related adverse effects and reactionsSolifenacin Succinate/Tamsulosin HydrochlorideBladder neck obstructionSolifenacin Succinate/Tamsulosin HydrochlorideBenign prostatic hyperplasiaDutasteride/Tamsulosin HydrochlorideBenign prostatic hyperplasiaTamsulosin HydrochlorideUrinary tract infectionTamsulosin HydrochlorideUrinary retentionTamsulosin HydrochlorideInguinal herniaTamsulosin HydrochlorideVoiding dysfunctionTamsulosin HydrochlorideLower urinary tract symptomsTamsulosin Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Tadalafil/Tamsulosin | Tier C — Watch / trade | - |
| Solifenacin Succinate/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
| Dutasteride/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
| Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-Hydroxy-2-ethoxybenzene→1,2-Dichloroethane→1-(2-Chloroethoxy)-2-ethoxybenzene→1,3-Dihydro-1,3-dioxoisoindole potassium salt→2-[2-(2-Ethoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione→2-(2-Ethoxyphenoxy)ethylamine
Solifenacin Succinate/Tamsulosin HydrochlorideOptimised routesteps: 3total yield: 20g(Tamsulosin Hydrochloride-065)
1-Hydroxy-2-ethoxybenzene→1,2-Dichloroethane→1-(2-Chloroethoxy)-2-ethoxybenzene→1,3-Dihydro-1,3-dioxoisoindole potassium salt→2-[2-(2-Ethoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione→2-(2-Ethoxyphenoxy)ethylamine
Dutasteride/Tamsulosin HydrochlorideOptimised routesteps: 3total yield: 20g(Tamsulosin Hydrochloride-065)
1-Hydroxy-2-ethoxybenzene→1,2-Dichloroethane→1-(2-Chloroethoxy)-2-ethoxybenzene→1,3-Dihydro-1,3-dioxoisoindole potassium salt→2-[2-(2-Ethoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione→2-(2-Ethoxyphenoxy)ethylamine
1-Hydroxy-2-ethoxybenzene→1,2-Dichloroethane→1-(2-Chloroethoxy)-2-ethoxybenzene→1,3-Dihydro-1,3-dioxoisoindole potassium salt→2-[2-(2-Ethoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione→2-(2-Ethoxyphenoxy)ethylamine
Intermediates available on this site
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.