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CAS 1542133-34-5
methyl (S,E)-6-((tert-butoxycarbonyl)amino)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-2-oxo-1,2-dihydropyridin-3-yl)amino)-7-oxohept-2-enoate
Codes: ZED-1227-008
Application context (from source-drug indications)
乳糜泻VilagletistatNon-alcoholic steatohepatitisVilagletistatLiver cirrhosisVilagletistat
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Vilagletistat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ZED-1227→3-nitropyridin-2-ol→tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate→2-(3-nitro-2-oxopyridin-1(2H)-yl)acetic acid→2-ethylbutan-1-amine→N-(2-ethylbutyl)-2-(3-nitro-2-oxopyridin-1(2H)-yl)acetamide→2-(3-amino-2-oxopyridin-1(2H)-yl)-N-(2-ethylbutyl)acetamide→(S,E)-2-((tert-butoxycarbonyl)amino)-7-methoxy-7-oxohept-5-enoic acid→methyl (S,E)-6-((tert-butoxycarbonyl)amino)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-2-oxo-1,2-dihydropyridin-3-yl)amino)-7-oxohept-2-enoate→(S)-5-(tert-butoxy)-4-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid→1-(tert-butyl) 5-methyl (tert-butoxycarbonyl)-L-glutamate→ZED-1227-011→ZED-1227-012→ZED-1227-013
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