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CAS 1622-55-5
6-thiatricyclo[8.4.0.0(3,7)]tetradeca-1(10),3(7),4,11,13-pentaen-2-one
Codes: (X)471701-1-b
Application context (from source-drug indications)
Influenza virus infectionNorketotifenAllergic conjunctivitisNorketotifenAllergic rhinitisNorketotifen
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Norketotifen | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
8,9-Dibromo-6-thiatricyclo[8.4.0.0(3,7)]tetradeca-1(10),3(7),4,11,13-pentaen-2-one→1-Methylpiperidn-4-ylmagnesium chloride→4-(1-Methyl-4-piperidinylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one→6-thiatricyclo[8.4.0.0(3,7)]tetradeca-1(10),3(7),4,11,13-pentaen-2-one→8-bromo-6-thiatricyclo[8.4.0.0(3,7)]tetradeca-1(10),3(7),4,8,11,13-hexaen-2-one→8-bromo-2-(1-methylpiperidin-4-yl)-6-thiatricyclo[8.4.0.0(3,7)]tetradeca-1(10),3(7),4,8,11,13-hexaen-2-ol→4-{8-bromo-6-thiatricyclo[8.4.0.0(3,7)]tetradeca-1(10),3(7),4,8,11,13-hexaen-2-ylidene}-1-methylpiperidine→Azacyclohexane→1-Methyl-4-[9-(piperidin-1-yl)-6-thiatricyclo[8.4.0.0(3,7)]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-ylidene]piperidine→1-methyl-4-[8-(piperidin-1-yl)-6-thiatricyclo[8.4.0.0(3,7)]tetradeca-1(10),3(7),4,8,11,13-hexaen-2-ylidene]piperidine→2-(1-Methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0(3,7)]tetradeca-1(14),3(7),4,10,12-pentaen-9-one
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 4-Oxo-9,10-dihydro-4H-benzo(4,5)-cyclohepta-(1,2b)thiophene Pharmaceutical Intermediates | On request | On request | On request | — |
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