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CAS 1622908-61-5
ethyl 4-(2-aminoacetamido)-3-methoxybenzoate hydrochloride
Codes: IDAS-013, IDAS-014
Application context (from source-drug indications)
Solid tumourIdasanutlinAcute myeloid leukaemiaIdasanutlinPolycythaemia veraIdasanutlinLeukaemiaIdasanutlinAcute lymphoblastic leukaemiaIdasanutlinNeuroblastomaIdasanutlin
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Idasanutlin | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(Z)-2-(4-chloro-2-fluoro-6-methylphenyl)-3-(3-chloro-2-fluorophenyl)acrylonitrile→4-amino-3-methoxybenzoic acid→ethyl 4-amino-3-methoxybenzoate→2-chloroacetyl chloride→ethyl 4-(2-aminoacetamido)-3-methoxybenzoate hydrochloride→ethyl 4-(2-aminoacetamido)-3-methoxybenzoate hydrochloride→3,3-dimethylbutanal→ethyl (E)-4-(2-((3,3-dimethylbutylidene)amino)acetamido)-3-methoxybenzoate→ethyl 4-((2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoate
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