← Back to patent-cliff list
CAS 1623085-79-9
(R)-3-aminobutan-1-ol (2S,3S)-2,3-dihydroxysuccinate
Codes: DOLU-023
Application context (from source-drug indications)
HIV infectionDolutegravir SodiumLabour and deliveryDolutegravir SodiumMycobacterium tuberculosis infectionDolutegravir SodiumHepatitisDolutegravir SodiumHerpesvirus infectionDolutegravir SodiumHepatic function declineDolutegravir Sodium
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Dolutegravir Sodium | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(2,4-difluorophenyl)methanamine→dimethyl 1-(2,2-dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate→1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid→(R)-3-aminobutan-1-ol (2S,3S)-2,3-dihydroxysuccinate→(4R,12aS)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid→(4R,12aS)-N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.