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CAS 1628836-08-7
(1R,2R)-2-amino-6-(4-nitrophenyl)-1-phenylhex-5-yn-1-ol hydrochloride
Codes: VIBE-020
Application context (from source-drug indications)
Overactive bladderVibegronUrinary incontinenceVibegron
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Vibegron | Tier C — Watch / trade | 2031 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-azatricyclo[4.2.1.02,5]non-7-en-4-one→(S)-methyl 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylate→pent-4-yn-1-ol→hex-5-ynal→tert-butyl (1-cyanopent-4-yn-1-yl)carbamate→tert-butyl (1-oxo-1-phenylhex-5-yn-2-yl)carbamate→tert-butyl ((1R,2R)-1-hydroxy-1-phenylhex-5-yn-2-yl)carbamate→1-iodo-4-nitrobenzene→(1R,2R)-2-amino-6-(4-nitrophenyl)-1-phenylhex-5-yn-1-ol hydrochloride→(R)-((2R,5S)-5-(4-aminobenzyl)pyrrolidin-2-yl)(phenyl)methanol→(S)-methyl 5-oxopyrrolidine-2-carboxylate
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | (1R,2R)-2-amino-6-(4-nitrophenyl)-1-phenylhex-5-yn-1-olhydrochloride Pharmaceutical Intermediates | On request | On request | On request | — |
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