CAS 163597-57-7

3-cyano-4-isobutoxybenzothioamide

Codes: FEBU-026

Application context (from source-drug indications)

HyperuricaemiaFebuxostatGoutFebuxostatIntracranial haemorrhageFebuxostatUlcerative colitisFebuxostatChronic renal impairmentFebuxostatPainFebuxostat

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Febuxostat	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

FebuxostatOptimised routesteps: 5total yield: 1.29 g

ethyl 2-chloro-3-oxobutanoate→1-bromo-2-methylpropane→ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate→2,4-dibromophenol→2,4-dibromo-1-isobutoxybenzene→4-isobutoxyisophthalonitrile→3-cyano-4-isobutoxybenzothioamide

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

Supplier	Product	Price band	MOQ	Lead time	Qualifications	Action
Qualified Partner — East China API Works	Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Pharmaceutical Intermediates	On request	On request	On request	—
Unibest Nantong cGMP Site	Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Pharmaceutical Intermediates	On request	On request	On request	—

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