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CAS 163706-58-9
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
Codes: CANG-010, CANG-026
Application context (from source-drug indications)
Coronary thrombosisCangrelor TetrasodiumMyocardial infarctionCangrelor TetrasodiumThrombosisCangrelor TetrasodiumAcute coronary syndromeCangrelor TetrasodiumCoronary artery lesionCangrelor TetrasodiumAtherosclerosisCangrelor Tetrasodium
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Cangrelor Tetrasodium | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(2R,3R,4R,5R)-2-(6-acetamido-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyl diacetate→(2-chloroethyl)(methyl)sulfane→(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(N-(2-(methylthio)ethyl)acetamido)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate→(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol→((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate→tributylamine (dichloromethylene)bis(phosphonate)→CANG-013→(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol→6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purine 1-oxide→(Z)-5-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-N'-hydroxy-1H-imidazole-4-carboximidamide→(2R,3R,4S,5R)-2-(6-amino-2-mercapto-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrate→3-chloro-1,1,1-trifluoropropane→(2R,3R,4S,5R)-2-(6-amino-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
(2S,3R,4R,5R)-5-(acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate→(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate→(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol→N-(2-(methylthio)ethyl)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-6-amine→tributylamine (dichloromethylene)bis(phosphonate)→2-thioxodihydropyrimidine-4,6(1H,5H)-dione→1,1,1-trifluoro-3-iodopropane→2-((3,3,3-trifluoropropyl)thio)pyrimidine-4,6-diol→5-nitro-2-((3,3,3-trifluoropropyl)thio)pyrimidine-4,6-diol→4,6-dichloro-5-nitro-2-((3,3,3-trifluoropropyl)thio)pyrimidine→4,6-dichloro-2-((3,3,3-trifluoropropyl)thio)pyrimidin-5-amine→6-chloro-2-((3,3,3-trifluoropropyl)thio)pyrimidine-4,5-diamine→6-chloro-2-((3,3,3-trifluoropropyl)thio)-9H-purine→2-aminoethanethiol hydrochloride
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | (2R,3S,4R,5R)-2-(hydroxyMethyl)-5-(6-((2-(Methylthio)ethyl)aMino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.