← Back to patent-cliff list
CAS 167095-12-7
(1E)-3-Ethoxy-3-oxo-1-phenyl-1-[(phenylcarbonyl)amino]prop-1-en-2-yl ethyl ethanedioate
Codes: (V)101438-50-a
Application context (from source-drug indications)
Breast cancerPaclitaxel/Encequidar mesylateAdenocarcinomaPaclitaxel/Encequidar mesylateAngiosarcomaPaclitaxel/Encequidar mesylateSolid tumourPaclitaxel/Encequidar mesylatePancreatic cancerPaclitaxelNon-small cell lung cancerPaclitaxelHodgkin's diseasePaclitaxelSeminomaPaclitaxelOvarian cancerPaclitaxelBreast cancerPaclitaxel
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Paclitaxel/Encequidar mesylate | Tier C — Watch / trade | - |
| Paclitaxel | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(±)-alpha-Aminophenylacetic acid→alpha-Chlorobenzaldehyde→2-Phenyl-2-(phenylformamido)acetic acid→1-(Chlorocarbonyl)formic acid ethyl ester→(1E)-3-Ethoxy-3-oxo-1-phenyl-1-[(phenylcarbonyl)amino]prop-1-en-2-yl ethyl ethanedioate→Ethyl 2-oxo-3-phenyl-3-[(phenylcarbonyl)amino]propanoate→(±)-Ethyl (2R,3S)-2-hydroxy-3-phenyl-3-[(phenylcarbonyl)amino]propanoate→(2R,3S)-2-Hydroxy-3-phenyl-3-(phenylformamido)propanoic acid
(±)-alpha-Aminophenylacetic acid→alpha-Chlorobenzaldehyde→2-Phenyl-2-(phenylformamido)acetic acid→1-(Chlorocarbonyl)formic acid ethyl ester→(1E)-3-Ethoxy-3-oxo-1-phenyl-1-[(phenylcarbonyl)amino]prop-1-en-2-yl ethyl ethanedioate→Ethyl 2-oxo-3-phenyl-3-[(phenylcarbonyl)amino]propanoate→(±)-Ethyl (2R,3S)-2-hydroxy-3-phenyl-3-[(phenylcarbonyl)amino]propanoate→(2R,3S)-2-Hydroxy-3-phenyl-3-(phenylformamido)propanoic acid
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.