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CAS 1701410-34-5
methyl 3-oxo-4-(2,2,2-trifluoroacetamido)-2,3-dihydrobenzofuran-7-carboxylate
Codes: PRUC-033
Application context (from source-drug indications)
ConstipationPrucalopride SuccinatePostoperative complicationPrucalopride SuccinateEnteral feeding intolerancePrucalopride SuccinateOpioid-induced constipationPrucalopride SuccinatePainPrucalopride SuccinateIntestinal pseudo-obstructionPrucalopride Succinate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Prucalopride Succinate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid→methyl 4-amino-2-hydroxybenzoate→methyl 2-hydroxy-4-(2,2,2-trifluoroacetamido)benzoate→methyl 3-(2-chloroacetyl)-2-hydroxy-4-(2,2,2-trifluoroacetamido)benzoate→methyl 3-oxo-4-(2,2,2-trifluoroacetamido)-2,3-dihydrobenzofuran-7-carboxylate→methyl 4-(2,2,2-trifluoroacetamido)-2,3-dihydrobenzofuran-7-carboxylate→methyl 5-chloro-4-(2,2,2-trifluoroacetamido)-2,3-dihydrobenzofuran-7-carboxylate
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