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CAS 170749-59-4

1-benzhydrylazetidin-3-yl 3-amino-3-iminopropanoate acetate

Codes: AZEL-006

Application context (from source-drug indications)

HypertensionOlmesartan Medoxomil/AzelnidipineHypertensionAzelnidipine

Source drugs (routes using this intermediate)

DrugTierExpiry
Olmesartan Medoxomil/AzelnidipineTier C — Watch / trade-
AzelnidipineTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Olmesartan Medoxomil/AzelnidipineOriginator routesteps: 4total yield: 2.17 g
diphenylmethanamine→2-(chloromethyl)oxirane→1-benzhydrylazetidin-3-ol→2-cyanoacetic acid→1-benzhydrylazetidin-3-yl 2-cyanoacetate→1-benzhydrylazetidin-3-yl 3-amino-3-iminopropanoate acetate→isopropyl (E)-2-(3-nitrobenzylidene)-3-oxobutanoate
AzelnidipineOriginator routesteps: 4total yield: 2.17 g
diphenylmethanamine→2-(chloromethyl)oxirane→1-benzhydrylazetidin-3-ol→2-cyanoacetic acid→1-benzhydrylazetidin-3-yl 2-cyanoacetate→1-benzhydrylazetidin-3-yl 3-amino-3-iminopropanoate acetate→isopropyl (E)-2-(3-nitrobenzylidene)-3-oxobutanoate

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