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CAS 1709-52-0
1-(4-aminophenyl)-N-methylmethanesulfonamide
Codes: SUMAT-001
Application context (from source-drug indications)
MigraineNaproxen Sodium/Sumatriptan SuccinateMigraine without auraNaproxen Sodium/Sumatriptan SuccinateCluster headacheSumatriptan SuccinateMigraineSumatriptan SuccinateSecondary headache disorderSumatriptan SuccinatePost-traumatic headacheSumatriptan Succinate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Naproxen Sodium/Sumatriptan Succinate | Tier C — Watch / trade | - |
| Sumatriptan Succinate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(4-aminophenyl)-N-methylmethanesulfonamide→1-(3-hydrazineylphenyl)-N-methylmethanesulfonamide→2-(phenylthio)acetaldehyde→(E)-N-methyl-1-(3-(2-(2-(phenylthio)ethylidene)hydrazineyl)phenyl)methanesulfonamide→N-methyl-1-(3-(phenylthio)-1H-indol-5-yl)methanesulfonamide→1-(1H-indol-5-yl)-N-methylmethanesulfonamide→dimethylamine→N,N-dimethyl-2-(5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)-2-oxoacetamide→1-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-N-methylmethanesulfonamide
1-(4-aminophenyl)-N-methylmethanesulfonamide→1-(3-hydrazineylphenyl)-N-methylmethanesulfonamide→2-(phenylthio)acetaldehyde→(E)-N-methyl-1-(3-(2-(2-(phenylthio)ethylidene)hydrazineyl)phenyl)methanesulfonamide→N-methyl-1-(3-(phenylthio)-1H-indol-5-yl)methanesulfonamide→1-(1H-indol-5-yl)-N-methylmethanesulfonamide→dimethylamine→N,N-dimethyl-2-(5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)-2-oxoacetamide→1-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-N-methylmethanesulfonamide
Intermediates available on this site
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