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CAS 1711-07-5
3-fluorobenzoyl chloride
Codes: Foslinanib-002
Application context (from source-drug indications)
Hepatocellular carcinomaFoslinanib肺神经内分泌癌FoslinanibNeuroendocrine carcinomaFoslinanibNeuroendocrine tumourFoslinanib胃肠胰神经内分泌肿瘤Foslinanib胰岛细胞腺瘤Foslinanib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Foslinanib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(6-amino-2,3-dimethoxyphenyl)ethan-1-one→3-fluorobenzoyl chloride→N-(2-acetyl-3,4-dimethoxyphenyl)-3-fluorobenzamide→2-(3-fluorophenyl)-5,6-dimethoxyquinolin-4(1H)-one→2-(3-fluorophenyl)-5-hydroxy-6-methoxyquinolin-4(1H)-one→tetrabenzyl diphosphate→tetrabenzyl (2-(3-fluorophenyl)-6-methoxyquinoline-4,5-diyl) bis(phosphate)→dibenzyl (2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl) phosphate→2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl dihydrogen phosphate→4(1H)-Quinolinone, 2-(3-fluorophenyl)-6-methoxy-5-(phosphonooxy)-, sodium salt (1:2)
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