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CAS 172152-35-1
2-[[(4-Methoxy-3-methylpyridin-2-yl)methyl]sulfanyl]-5-(1H-pyrrol-1-yl)-1H-benzimidazole2-(((4-methoxy-3-methylpyridin-2-yl)methyl)thio)-5-(1H-pyrrol-1-yl)-1H-benzo[d]imidazole
Codes: Sodium ilaprazole-009, ILAP-007
Application context (from source-drug indications)
Peptic ulcerSodium ilaprazolePeptic ulcer bleedingSodium ilaprazoleDuodenal ulcerSodium ilaprazoleGastric ulcerSodium ilaprazolePeptic oesophagitisSodium ilaprazoleDuodenal ulcerIlaprazoleGastro-oesophageal reflux diseaseIlaprazolePeptic ulcer bleedingIlaprazoleOesophagitisIlaprazole
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Sodium ilaprazole | Tier C — Watch / trade | - |
| Ilaprazole | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-Nitro-1,4-phenylenediamine→2,5-Dimethoxytetrahydrofuran→2-Nitro-4-(1H-pyrrol-1-yl)aniline→4-(1H-Pyrrol-1-yl)benzene-1,2-diamine→Carbon disulfide→5-(1H-Pyrrol-1-yl)-1H-benzimidazole-2-thiol→2-(Chloromethyl)-4-methoxy-3-methylpyridine→2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrogen chloride→2-[[(4-Methoxy-3-methylpyridin-2-yl)methyl]sulfanyl]-5-(1H-pyrrol-1-yl)-1H-benzimidazole
2,3-Lutidine→2,3-Dimethyl-1-oxidopyridin-1-ium→2,3-Dimethyl-4-nitropyridine N-oxide→4-methoxy-2,3-dimethyl-1-oxidopyridin-1-ium→(4-methoxy-3-methylpyridin-2-yl)methanol→5-nitro-1H-benzimidazole-2-thiol→5-amino-1H-benzimidazole-2-thiol→Tetrahydro-2,5-dimethoxyfuran→2-(Chloromethyl)-4-methoxy-3-methylpyridine→5-(1H-Pyrrol-1-yl)-1H-benzimidazole-2-thiol→2-[[(4-Methoxy-3-methylpyridin-2-yl)methyl]sulfanyl]-5-(1H-pyrrol-1-yl)-1H-benzimidazole
2-[(S)-(4-Methoxy-3-methylpyridin-2-yl)methanesulfinyl]-5-(1H-pyrrol-1-yl)-1H-benzimidazole→2-[(R)-(4-Methoxy-3-methylpyridin-2-yl)methanesulfinyl]-5-(1H-pyrrol-1-yl)-1H-benzimidazole→2-[[(4-Methoxy-3-methylpyridin-2-yl)methyl]sulfanyl]-5-(1H-pyrrol-1-yl)-1H-benzimidazole
2-nitrobenzene-1,4-diamine→2,5-dimethoxytetrahydrofuran→2-nitro-4-(1H-pyrrol-1-yl)aniline→4-(1H-pyrrol-1-yl)benzene-1,2-diamine→5-(1H-pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol→2-(chloromethyl)-4-methoxy-3-methylpyridine hydrochloride→2-(((4-methoxy-3-methylpyridin-2-yl)methyl)thio)-5-(1H-pyrrol-1-yl)-1H-benzo[d]imidazole→Ilaprazole
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