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CAS 1808952-22-8
(R)-1-(3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-3-carboxamide
Codes: TREL-018
Application context (from source-drug indications)
Type 2 diabetesTrelagliptin SuccinateDiabetesTrelagliptin Succinate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Trelagliptin Succinate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile→succinic acid→nicotinamide→1,4,5,6-tetrahydropyridine-3-carboxamide→(R)-piperidine-3-carboxamide 4-methylbenzenesulfonate→(R)-1-(3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-3-carboxamide
Intermediates available on this site
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