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CAS 1867-66-9
(±)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride
Codes: (Xa)270899-4-a
Application context (from source-drug indications)
Major depressive disorderEsketamine HydrochlorideSuicidal ideationEsketamine HydrochlorideDepressive disorderEsketamine HydrochlorideAnaesthesiaEsketamine HydrochlorideTreatment-resistant depressionEsketamine HydrochloridePainEsketamine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Esketamine Hydrochloride | Tier B — Position early | 2029 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Iodomethane→Chlorocyclopentane→1-Chloro-2-cyanobenzene→(2-Chlorophenyl)(cyclopentyl)methanone→2-Chlorobenzoyl chloride→Cyclopentene→(1-Bromocyclopentyl)(2-chlorophenyl) ketone→Aminomethane→1-[(E)-(2-Chlorophenyl)(methylimino)methyl]cyclopentan-1-ol hydrogen chloride→(±)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride→2-(2-Chlorophenyl)-2-(methylamino)cyclohexan-1-one→(2S)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
Intermediates available on this site
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