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CAS 190662-30-7

[(8S,13S,14S,17R)-17-Hydroxy-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-yl]acetonitrile

Codes: (III)90248-6-a

Application context (from source-drug indications)

ContraceptionDienogest/Estradiol ValerateMenorrhagiaDienogest/Estradiol ValerateContraceptive useDienogest/Estradiol ValeratePelvic painDienogest/Estradiol ValerateHeadacheDienogest/Estradiol ValerateDysmenorrhoeaDienogest/Estradiol ValerateContraceptionDienogestEndocrine system disorderDienogestEndometriosisDienogestAdenomyosisDienogestPainDienogest

Source drugs (routes using this intermediate)

DrugTierExpiry
Dienogest/Estradiol ValerateTier C — Watch / trade-
DienogestTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Dienogest/Estradiol ValerateOptimised routesteps: 2total yield: /
[(8S,13S,14S,17R)-17-Hydroxy-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-yl]acetonitrile→17-Oxo-estradiene→Acetonitrile anhydrous
DienogestOptimised routesteps: 2total yield: /
[(8S,13S,14S,17R)-17-Hydroxy-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-yl]acetonitrile→17-Oxo-estradiene→Acetonitrile anhydrous

Intermediates available on this site

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