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CAS 199468-20-7
(S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one (2R,3R)-2,3-dihydroxysuccinate
Codes: ESKE-003
Application context (from source-drug indications)
Major depressive disorderEsketamine HydrochlorideSuicidal ideationEsketamine HydrochlorideDepressive disorderEsketamine HydrochlorideAnaesthesiaEsketamine HydrochlorideTreatment-resistant depressionEsketamine HydrochloridePainEsketamine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Esketamine Hydrochloride | Tier B — Position early | 2029 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one→(2R,3R)-2,3-dihydroxysuccinic acid→(S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one (2R,3R)-2,3-dihydroxysuccinate→(S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
Intermediates available on this site
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