CAS 19982-07-1

N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)acetamide

Codes: MEMA-003

Application context (from source-drug indications)

Alzheimer's diseaseMemantine Hydrochloride/Donepezil HydrochlorideAlzheimer's diseaseMemantine HydrochlorideTraumatic brain injuryMemantine HydrochlorideTrichotillomaniaMemantine HydrochlorideSchizophreniaMemantine HydrochlorideLung cancerMemantine HydrochlorideSmall cell lung cancerMemantine Hydrochloride

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Memantine Hydrochloride/Donepezil Hydrochloride	Tier C — Watch / trade	-
Memantine Hydrochloride	Tier B — Position early	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Memantine Hydrochloride/Donepezil HydrochlorideOriginator routesteps: 3total yield: 3.5 g

(1r,3r,5s,7s)-1,3-dimethyladamantane→(1r,3R,5S,7r)-1-bromo-3,5-dimethyladamantane→N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)acetamide

Memantine Hydrochloride/Donepezil HydrochlorideOptimised routesteps: 2total yield: 320 g

(1r,3r,5s,7s)-1,3-dimethyladamantane→N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)acetamide

Memantine HydrochlorideOriginator routesteps: 3total yield: 3.5 g

(1r,3r,5s,7s)-1,3-dimethyladamantane→(1r,3R,5S,7r)-1-bromo-3,5-dimethyladamantane→N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)acetamide

Memantine HydrochlorideOptimised routesteps: 2total yield: 320 g

(1r,3r,5s,7s)-1,3-dimethyladamantane→N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)acetamide

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.