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CAS 2033-24-1

2,2-Dimethyl-1,3-dioxane-4,6-dione2,2-dimethyl-1,3-dioxane-4,6-dione

Codes: (IV)109067-6-a, (VIII)1225102-2-a, ERTA-010

Application context (from source-drug indications)

HypertensionOlmesartan Medoxomil/Amlodipine orotateEssential hypertensionValsartan/Amlodipine OrotateVariant anginaAmlodipine OrotateHypertensionAmlodipine OrotateIschaemic heart diseaseAmlodipine OrotateStable anginaAmlodipine OrotateNon-small cell lung cancerFulzerasibColorectal cancerFulzerasibSolid tumourFulzerasibHypertensionAmlodipine CamsylateComplicated skin and skin structure infectionErtapenem SodiumIntra-abdominal infectionErtapenem SodiumBacteraemiaErtapenem SodiumUrinary tract infectionErtapenem SodiumCommunity-acquired pneumoniaErtapenem SodiumPyelonephritisErtapenem Sodium

Source drugs (routes using this intermediate)

DrugTierExpiry
Olmesartan Medoxomil/Amlodipine orotateTier C — Watch / trade-
Valsartan/Amlodipine OrotateTier C — Watch / trade-
Amlodipine OrotateTier C — Watch / trade-
FulzerasibTier C — Watch / trade-
Amlodipine CamsylateTier C — Watch / trade-
Ertapenem SodiumTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

FulzerasibOptimised routesteps: 5total yield: /
2,6-Dichloronicotinic acid→2-Isopropyl-4-methylpyridin-3-amine→6-Chloro-2-[(2-isopropyl-4-methyl-3-pyridyl)amino]pyridine-3-carboxylic acid→5,6-Dichloro-2-[(2-isopropyl-4-methyl-3-pyridyl)amino]pyridine-3-carboxylic acid→5,6-Dichloro-2-[[4-methyl-2-(propan-2-yl)pyridin-3-yl]amino]pyridine-3-carbonyl chloride→3-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-oxopropanoic acid→(alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol→2,2-Dimethyl-1,3-dioxane-4,6-dione→3-Oxo-3-[(1S)-1-phenylethoxy]propanoic acid→(1S)-Methyl phenyl carbinol→(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl 3-(5,6-dichloro-2-[[4-methyl-2-(propan-2-yl)pyridin-3-yl]amino]pyridin-3-yl)-3-oxopropanoate→(1S)-1-Phenylethyl 3-(5,6-dichloro-2-[[4-methyl-2-(propan-2-yl)pyridin-3-yl]amino]pyridin-3-yl)-3-oxopropanoate→6,7-Dichloro-4-hydroxy-1-(2-isopropyl-4-methyl-3-pyridyl)-1,8-naphthyridin-2-one→3-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexoxy]-3-oxo-propanoic acid→(-)-(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol→(1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl 3-(5,6-dichloro-2-[[4-methyl-2-(propan-2-yl)pyridin-3-yl]amino]pyridin-3-yl)-3-oxopropanoate

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.