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CAS 207557-35-5
(S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile
Codes: VILD-005
Application context (from source-drug indications)
Type 2 diabetesVildagliptinSchizophreniaVildagliptinDyslipidaemiaVildagliptinInsulin resistanceVildagliptinType 1 diabetesVildagliptinDiabetesVildagliptin
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Vildagliptin | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(S)-pyrrolidine-2-carboxamide→2-chloroacetyl chloride→(S)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide→N-(chloromethylene)-N-methylmethanaminium chloride→(S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile→(1s,3r,5R,7S)-3-aminoadamantan-1-ol→(3s,5s,7s)-adamantan-1-amine→(1r,3s,5R,7S)-3-nitroadamantan-1-amine
2-chloroacetyl chloride→(S)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide→(S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile→(S)-pyrrolidine-2-carboxylic acid→(2-chloroacetyl)-L-proline
Intermediates available on this site
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