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CAS 2114320-34-0

Ethyl 4-(3,4-dichlorophenyl)-4-phenylbutanoate

Codes: Sertraline Hydrochloride-160

Application context (from source-drug indications)

Obsessive-compulsive disorderSertraline Citrate

Source drugs (routes using this intermediate)

DrugTierExpiry
Sertraline CitrateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Sertraline CitrateOptimised routesteps: 4total yield: /
4-(3,4-Dichlorophenyl)-1-tetralone→1,2-Dichloro-4-iodobenzene→(3,4-Dichlorophenyl)(iodido)zinc→2-Bromoacetic acid ethyl ester→Ethenylbenzene→Ethyl 4-(3,4-dichlorophenyl)-4-phenylbutanoate→(3,4-Dichlorophenyl)(phenyl)methanol→(1-Ethoxycyclopropoxy)trimethylsilane

Intermediates available on this site

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